Other heavy and explosive weapons like the Detonator or Grenade Launcher can blow himself to pieces), Ignore conventional durability with the Hand Cannon and the Devil Horns, even higher with preparation time (Can craft, modify, and upgraded weapons that have much stronger firepower than his regular weapons. ![]() Traveled through Tau Volantis, a planet which has a surface inundated with Markers, and was unaffected), Poison Manipulation (Isaac’s RIG is airtight, and when in the presence of breathable toxins it self-seals and relies on internal air supplies), Sleep Manipulation (One of the Suits Isaac has is able to inject stimulants into his bloodstream to prevent any fatigue), Cold and Hot temperatures (via his suits), Radiation Manipulation (His suit protected him from the highly radioactive orbs from the USS Valer's weapons), Acid Manipulation (His suits can resist a Puker's corrosive bile)Īttack Potency: Building level+ (Can fight and damage enemies who can harm him), higher with weapons (His weapons are effectively stronger than his physical blows. Resistance to Mind Manipulation and Madness Manipulation (Type 2 and 3 because of his strong will and high intelligence, Isaac can resist telepathic insanity inducement by the Markers and Brethren Moons), Biological Manipulation (Unaffected by the Marker Signal, which can turn even living tissue into necromorph flesh given enough time.
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